论文部分内容阅读
目的超声评价瑞舒伐他汀逆转颈动脉硬化斑块的疗效。方法从2009年5月至2010年6月我院入院治疗的颈动脉硬化症患者112例被随机分为实验组(n=60)和对照组(n=52),对照组给予常规治疗,实验组使用瑞舒伐他汀治疗。结果实验组的HDL-C和ALT显着上升,LDL-C、TG、TC、CRP和CIMT、RI显着下降,两组临床效果相比具有显著性差异(P<0.05)。结论瑞舒伐他汀能显着逆转颈动脉硬化斑块,明显提高疗效,值得在临床上应用和推广。
Objective To evaluate the efficacy of rosuvastatin on carotid atherosclerotic plaques by ultrasound. Methods One hundred and twelve patients with carotid atherosclerosis admitted to our hospital from May 2009 to June 2010 were randomly divided into experimental group (n = 60) and control group (n = 52). The control group was given routine treatment, and the experiment Groups were treated with rosuvastatin. Results The levels of HDL-C and ALT in the experimental group were significantly increased, while the levels of LDL-C, TG, TC, CRP, CIMT and RI were significantly decreased in the experimental group compared with those in the experimental group (P <0.05). Conclusion Rosuvastatin can significantly reverse the carotid plaque, significantly improve the efficacy, it is worth in the clinical application and promotion.