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研究表明,采用配偶淋巴细胞进行同种免疫治疗,对防止不同原因复发性流产(RSA)妇女再次妊娠失败有效;对同种免疫治疗后妊娠成功的妇女进行体外淋巴细胞反应的分析,发现其血清中有封闭因子存在。人类某些不明原因的RSA是因母体不能对胎儿产生免疫耐受所致,预先采用配偶的淋巴细胞进行免疫治疗可促进保护性免疫耐受的产生。最近研究发现,人类在接受移植长达29年时受者体内各部位仍有小量的供者细胞存在(即微量嵌合)。
Studies have shown that using spleen lymphocytes for alloimmunotherapy is effective in preventing the recurrence of pregnancy failure in women of recurrent spontaneous abortion (RSA) of different causes. Analysis of the in vitro lymphocyte reaction of women who have succeeded in pregnancy after alloimmunization showed that serum There is a closure factor in existence. Some unknown human RSA is due to the mother can not be immune tolerance caused by the fetus, pre-use of spleen lymphocytes for immunotherapy can promote protective immune tolerance. Recent studies have found that humans still have a small number of donor cells (ie, microchips) remaining in various parts of the recipient for up to 29 years after transplantation.