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目的:观察荷丹楂泽饮联合阿托伐他汀钙片治疗高脂血症的临床疗效。方法:将60例高脂血症患者随机分为2组,各30例。对照组单纯给予阿托伐他汀钙片治疗;观察组在对照组治疗基础上加服荷丹楂泽饮治疗。2组均以4周为1疗程,1疗程后评判疗效。于治前1周及疗程结束后2周接受血清甘油三酯(TG)、总胆固醇(TC)、低密度及高密度脂蛋白胆固醇(LDLC、HDL-C)水平检测,观察不良反应。结果:总有效率观察组93.33%,对照组73.33%,2组比较,差异有统计学意义(P<0.01)。治疗后,2组HDL-C、LDL-C、TG、TC均明显下降,与治疗前比较,差异有统计学意义(P<0.05);治疗后观察组各项指标均低于对照组,2组比较,差异均有统计学意义(P<0.05)。2组不良反应发生率比较,差异有统计学意义(P<0.05)。结论:荷丹楂泽饮联合阿托伐他汀钙片治疗高脂血症可显著改善患者血脂水平,缓解临床症状,临床疗效明显,无不良反应。
Objective: To observe the clinical efficacy of hantosanzee combined with atorvastatin calcium in the treatment of hyperlipidemia. Methods: 60 cases of hyperlipidemia were randomly divided into two groups, each 30 cases. The control group was treated with atorvastatin calcium alone; the observation group was treated with the combination of hollyhock and hawthorn on the basis of the control group. 2 groups were 4 weeks for a course of treatment, after a course of treatment evaluation. Serum triglyceride (TG), total cholesterol (TC), low-density and high-density lipoprotein cholesterol (LDL-C) levels were measured at 1 week before treatment and 2 weeks after treatment. Adverse reactions were observed. Results: The total effective rate was 93.33% in the observation group and 73.33% in the control group. There was significant difference between the two groups (P <0.01). After treatment, the levels of HDL-C, LDL-C, TG and TC in the two groups were significantly decreased compared with those before treatment (P <0.05). After treatment, the indexes in the observation group were all lower than those in the control group The differences were statistically significant (P <0.05). The incidence of adverse reactions in the two groups, the difference was statistically significant (P <0.05). Conclusion: The combination of hollytrin and atorvastatin calcium can significantly improve the level of blood lipids, relieve the clinical symptoms, and has obvious clinical curative effect and no adverse reactions.