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采用 Ｅ Ｌ Ｉ Ｓ Ａ 法检测２０ 例格林巴利综合征（ Ｇ Ｂ Ｓ） 患者血清及脑脊液中 Ｉｇ Ｍ Ｇ Ｍ１ 、 Ｉｇ Ｇ Ｇ Ｍ１ 抗体水平。结果表明， Ｇ Ｂ Ｓ 患者血清及脑脊液中 Ｉｇ Ｍ Ｇ Ｍ１ 、 Ｉｇ Ｇ Ｇ Ｍ１ 抗体均明显高于对照组（ Ｐ＜ ００１） ；病情轻重分级之间 Ｇ Ｍ１ 抗体水平无明显差别（ 均 Ｐ＞ ００５） 。 Ｇ Ｂ Ｓ 患者周围和鞘内均存在高滴度的 Ｇ Ｍ１ 抗体，并可能在 Ｇ Ｂ Ｓ的病理过程中起重要作用。
The levels of Ig MG M1 and Ig GG M1 antibodies in serum and cerebrospinal fluid of 20 patients with Guillain-Barre syndrome (G B S) were detected by E L I S A method. The results showed that Ig M G M1 and Ig G G M1 antibodies in serum and cerebrospinal fluid of patients with G B S were significantly higher than those of the control group (P <001). There was no significant difference in G M 1 antibody levels between severity grading All P> 005). High GG antibodies were present both in the surrounding and intrathecally of G B S patients and may play an important role in the pathological process of G B S.