A novel series of compounds obtained by fusing the cholinesterase inhibitor donepezil and the antioxidant ebselen[1] were designed as multi-target-directed ligands against Alzheimers disease(AD).
DNA topoisomerase Ⅱ(TopoⅡ)are the targets of a variety of clinical agents which can manage the topological state of DNA.TopoⅡ poisons,such as Etoposide,induce tumor cell death by causing DNA strand br
A novel organic-inorganic hybrids,the so-called cerasomes has been synthesized by combination of sol-gel reaction and self-assembly of a molecular which is analogous to lipids.Firstly,the cerasome for