Ubiquitin aggregates and interacts with alpha-synuclein

来源 :2nd International Neural Regeneration Symposium(INRS2012)(第二 | 被引量 : 0次 | 上传用户:tiancejiangjun
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Parkinsons disease and dementia with Lewy bodies are characterized by the accumulation of abnormal α-synuclein and ubiquitin in protein aggregates forming Lewy bodies and Lewy neurites.
其他文献
This study sought to observe the effect of levetiracetam therapy for dyskinetic cerebral palsy.We selected patients with dyskinetic cerebral palsy randomly (outpatients and hospital patients from the
Lactoferrin, an iron-binding glycoprotein containing terminal sialic acid residues, is secreted in milk.Lactoferrin is synthesized in the brains of humans suffering from Alzheimers dementia, and in a
Lead is a risk to infants during early development, thus it is important to evaluate the environment of pregnant mothers and infants by multi-linear regression analysis.This prospective study assessed
Cerebral ischemia (stroke) is the second leading cause of death worldwide among numerous cardio-cerebrovascular diseases, which ranks second only to coronary heart diseases.
Research on autophagy as a mechanism for regulating cell death or survival has generated huge interest in recent years.Although both autophagy and apoptosis can function independently from each other,
The PAX6, a highly conserved transcriptional regulator, critically regulates axon guidance, differentiation of neurons from glia, and neuronal migration.
Ischemic strokes can cause irreversible locally restricted loss of neuronal circuitry and supporting glial cells with consecutive functional deficits and disabilities.
Several degradable and absorbable nerve conduits, such as those produced with collagen, chitosan and poly-glycolic acid, have been used for clinical applications.
Expansion of polyglutamine repeats is the cause of at least nine inherited human neurodegenerative disorders, including Huntingtons disease.It is widely accepted that deregulation of the transcription
Optic nerve injury induces retina ganglion cells (RGC) death and loss of visual function in mammals, but not in low vertebrates such as zebrafish.Detailed RGC survival and regeneration in adult zebraf