【摘 要】
：
Background.The purpose of this study was to determine the features of the eldedy patient with nasopharyngeal carcinoma (NPC).Methods.The medical records of 212 patients with NPC, aged >65 years, and r
【机 构】
：
Department of Radiation 0ncology, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Un
论文部分内容阅读
Background.The purpose of this study was to determine the features of the eldedy patient with nasopharyngeal carcinoma (NPC).Methods.The medical records of 212 patients with NPC, aged >65 years, and receiving radiotherapy were retrospectively reviewed.Comorbidity was rated using the Charlson Comorbidity Index (CCI).Results.Twenty-four patients (11.3%) scored >3 and 188 patients (88.7%) scored <3 rated by CCI.The median actuarial irradiated dose of the nasopharynx was 72 Gy (range, 20-94 Gy) with 87.3% patients receiving >70 Gy.0ne hundred fifty-four patients had stage Ⅲ/Ⅳ disease.The actuarial local control, cancer-specific survival (CSS), and overall survival (0S) rates at 5 years were 68.8%, 63.5%, and 47.0%, respectively.0n multivariate analysis, stage (hazard ratio [HR], 1.489;95% confidence interval [CI], 1.168-1.897;p =.001), the technique of radiotherapy (HR,0.674;95% CI, 0.476-0.953;p =.025), and anemia (HR, 3.081;95% CI,1.624-5.845;p =.001) were independent prognostic factors.Conclusion.The elderly patients with NPC may inherently predict poor outcomes.
其他文献
患者,女,83岁,2014年1月因"咳嗽、胸闷"就诊于当地医院,查体：体型偏瘦,呼吸动度两侧不对称,语颤左侧减弱,,左肺呼吸音减低,心律齐,各瓣膜听诊区未闻及杂音."高血压"病史10年,余无特殊.胸部CT显示,纵隔占位,最大截面7.8cm×11.4cm,边界不清,包绕升主动脉、肺动脉干,突入左肺野;纵隔内、双肺门、心包左侧壁、心包横膈区、左侧内乳区多发淋巴结肿大;双侧胸腔积液.影像诊断：巨大侵袭性
目的：探讨γ-体部立体定向放疗(stereotic body radiation therapy withγ-knife,γ-SBRT)配合热疗及替古奥治疗局部晚期胰腺癌疗效..方法：2012年6月-2013年4月,收治54例胰腺癌患者,30侧行γ-SBRT配合热疗,24例行γ-SBRT配合热疗及替吉奥治疗.结果：治疗后3个月总的有效率为79.6％(43/54).γ-SBRT配合热疗的1年生存率为
Background: In recent years, chemotherapy, radiotherapy, and targeted drugs have been respectively used in nasopharyngeal carcinoma.In our research, we combined all of them for better curative effects
盐酸羟考酮缓释片作为一种新型的强阿片类镇痛药,镇痛效果确切、口服安全性高、不良反应轻微,持续应用可提高癌痛患者的生存质量,是临床治疗中重度癌痛的首选药物之一.针对盐酸羟考酮缓释片治疗癌痛的药理特点,近年国内外将其用于癌痛治疗过程中的剂量调整,取得了很好的效果.
Objective To evaluate concurrent chemotherapy for T4 classification nasopharyngeal carcinoma (NPC) treated by intensity-modulated radiotherapy (IMRT).Methods From July 2004 to June 2011,180 non-metast
本研究主要是评价接受根治性切除和辅助化疗的pⅢA-N2期非小细胞肺癌(NSCLC)患者,进一步接受术后三维适形放疗(3DCRT)对生存和复发模式的影响.从2009.1.1到2013.5.31,所有患者均接受根治性肺叶切除的pⅢA-N2NSCLC患者在完成4周期以顺铂为基础的联合化疗后进行全面复查,未出现肿瘤复发转移的患者被随机分入术后放疗(PORT)组和对照组.入组≥2年的患者纳入本次分析.POR
分析Ⅳ期肺腺癌采用选择性放疗联合/或靶向治疗的疗效.分析本院2009年6月1日起,Ⅳ期肺腺癌接受肺原发病灶和关键转移病灶选择性放疗联合/或靶向治疗的患者共50例,其中单纯应用小分子靶向药物(表皮生长因子受体酪氨酸激酶抑制剂,EGFR-TKI)7例,单纯选择性放疗患者18例,选择性放疗联合EGFR-TKI25例.小分子靶向药物使用时间1～44月,中位时间14月.放疗方案为：体部伽马刀技术,70％等剂
Objective: To evaluate the long-term survival outcomes and toxicity of a larger series of patients with non-metastatic T4 classification nasopharyngeal carcinoma (NPC) treated with intensity-modulated
For patients with locoregionally advanced nasopharyngeal carcinoma (NPC), radiotherapy, chemotherapy and even targeted therapy are widely accepted treatments.These treatments, although they mostly ach