bioinformaticS相关论文
An EST-based search followed by molecular identification for potential antimicrobial peptides in the
Brassicanapuswas the third leading source of vegetable oil in the world after only soya bean and oil palm.The developmen......
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Identification of genome-wide nucleotide sites associated with mammalian virulence in influenza A vi
The virulence of influenza viruses is a complex multigenic trait. Previous studies about the virulence determinants of i......
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目的分析1个遗传性蛋白C(protein C，PC)缺陷症家系的表型和基因变异。方法检测先证者及其家系成员(共3代7人)的血浆蛋白C活性(prote......
目的分析人呼吸道合胞病毒(human respiratory syncytial virus，HRSV)感染HEp-2细胞后差异性表达的基因，为发现HRSV防治的潜在靶点提......
目的通过生物信息学对先天性小耳畸形基因调控网络进行分析。方法采用安捷伦全基因组外显子微阵列芯片鉴定2017年5月至2018年8月中......
宏基因组测序（mNGS）在新发突发传染病以及常规检验阴性的感染性疾病诊断中发挥了重要作用。近期，国内相继发表了多个共识阐述了临床应......
Comparative proteomes change and possible role in different pathways of microRNA-21a-5p in a mouse m
Our previous study found that microRNA-21a-5p (miR-21a-5p) knockdown could improve the recovery of motor function after ......
Long noncoding RNA (lncRNA) regulates the proliferation and migration of human retinal endothelial cells, as well as ret......
Objective: To obtain the key genes and signal pathways of diabetic peripheral neuropathy (DPN) through bioinformatics an......
目的:探讨前交叉韧带(anterior cruciate ligament,ACL)离断联合半月板切除诱发的骨关节炎(osteoarthritis,OA)的基因表达和生物过......
目的利用生物信息学方法对公共基因数据库微阵列表达谱进行分析，确定条件性恐惧记忆的关键基因。方法从Gene Expression Omnibus(GE......
目的 扩增大鼠细胞因子信号转导抑制因子-1(SOCS-1)基因,利用生物信息学方法预测其结构和功能特征,为进一步的实验研究提供理论指......
目的利用生物信息学方法分析脓毒症患者骨骼肌细胞基因标志物的特征。方法从美国国立生物技术信息中心（NCBI）的基因表达数据库（GEO）中......
目的利用microRNA（miRNA）表达谱芯片探索大黄素对脓毒症小鼠肠道miRNA表达的调控作用。方法通过盲肠结扎穿孔法建立脓毒症模型，42只c5......
目的:通过生物信息学分析HOTAIR与hsa-miR-148b-3p是否存在结合,进而通过细胞学实验验证在乳腺癌细胞系中两者互作关系如何,为下一......
目的 研究广州地区新生儿感染人巨细胞病毒(HCMV)临床低传代株UL136基因的序列特征与基因多态性.方法 从10例广州感染新生儿体内分......
To investigate the relationship between transcription factor and the change of protein expression levels in heart failur......
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Objective miR-22 is highly active in breast cancer, especially in the luminal B and HER2 subtypes. However, the detailed......
目的:探讨microRNA-23b(miR-23b)表达异常与心脏发育缺陷的关系。方法 :收集人胚胎心肌组织和发育中的小鼠胚胎心肌组织,0.9%二甲......
Background:GASA (Giberellic Acid Stimulated in Arabidopsis) gene family plays a crucial role in the phytohormone signali......
Identification of potential immune-related prognostic biomarkers of lung cancer using gene co-expres
Objective The objective of this study was to identify new carcinogenetic hub genes and develop the integration of differ......
Differential expression of non-coding RNA after traumatic spinal cord injury (TSCI) is closely related to the pathophysi......
Complex pathological changes occur during the development of spinal cord injury (SCI), and determining the underlying mo......
The m6A methylation landscape stratifies hepatocellular carcinoma into 3 subtypes with distinct meta
Objective:Epigenetic aberration plays an important role in the development and progression of hepatocellular carcinoma (......
利用同源序列法,本实验以拟南芥DNA去甲基化酶ROS1的序列成功在玉米Maize Sequence网站获得玉米同源序列,并利用生物信息学的方法......
目的应用生物信息学软件预测幽门螺杆菌CagA基因编码蛋白的结构和功能。方法从NCBI数据库获取CagA基本的基因信息;应用ProtParam,S......
Background:Reproducibility is a defining feature of a scientific discovery.Reproducibility can be at different levels fo......
Background:More and more high-throughput datasets are available from multiple levels of measuring gene regulations.The r......
The complex pattern of cancer evolution poses a huge challenge to precision oncology.Longitudinal sequencing of tumor sa......
With the development of high throughput sequencing and single-cell genomics technologies,many uncultured bacterial commu......
The rapid development of high-throughput sequencing techniques has led biology into the big-data era.Data analyses using......
Objective To investigate the effect of c-fos gene silencing on differentially expressed proteins (DEPs) in human bronchi......
Leaf color has been considered an important agronomic trait in rice (Oryza sativa L.) for a long time. The changes in le......
Objective:To identify the potential role and prognostic value of LINC01614 in gastric cancer. Methods: qRT-PCR was appli......
目的分析新疆细粒棘球蚴EgAgB8/3蛋白氨基酸序列,了解该蛋白特性,预测其抗原表位,为进一步研究和选择包虫病免疫学诊断与防治的最......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的采用生物信息学方法预测has-miR-26b、has-miR-1972、has-miR-4485、has-miR-4498和has-miR-4743的靶基因，并分析其所参与的生......
序列比对是生物信息学中最基本、最重要的操作,通过序列比对可以发现生物序列中的功能、结构和进化的信息。BLAST算法是序列比对中......
目的采用生物信息学方法预测hsa_circRNA_102802和hsa_circRNA_104597相对应的miRNA的靶基因，并分析其所参与的生物学过程及信号通......
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目的检测侵袭性牙周炎（aggressive periodontitis，AgP）患者牙龈组织与健康牙龈中长链非编码RNA（long non-coding RNA，lncRNA）的差异性表......
Identification, Characterization, and Expression of P450 Gene Encoding CYP6BQ13v2 from the Red Flour
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
High-throughput sequencing of highbush blueberry transcriptome and analysis of basic helix-loop-heli
The highbush blueberry(Vaccinium corymbosum),Duke,was used to construct a de novo transcriptome sequence library and to ......
ObjectiveTo discover and identify differentially expressed genes associated with colorectal adenoma formation and the ro......
