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[期刊论文] 作者:Zongbing Hao,Rui Wang,Haigang Ren,Guanghui Wang, 来源:神经科学通报(英文版) 年份:2020
Since the discovery of the C9ORF72 gene in 2011,great advances have been achieved in its genetics and in identifying its role in disease models and pathological...
[期刊论文] 作者:Dan Wu,Zongbing Hao,Haigang Ren,Guanghui Wang, 来源:神经科学通报(英文版) 年份:2018
Autophagy is an evolutionarily-conserved self-degradative process that maintains cellular homeostasis by eliminating protein aggregates and damaged organelles.Recently,vesicle-associated membrane protein-associated protein B (VAPB),which is......
[期刊论文] 作者:Rui Wang,Xingyun Xu,Zongbing Hao,Shun Zhang,Dan Wu,Hongyang Sun,Chenchen Mu,Haigang Ren,Guanghui Wang, 来源:神经科学通报(英文版) 年份:2019
GGGGCC repeat expansions in the C9ORF72 gene are the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia (c9ALS/FrD).It has been reported that hexanucleotide repeat expansions in C9ORF72 produce five dipeptide rep......
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