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[会议论文] 作者：Shi-Long Zhong,
来源：第16届中国南方国际心血管病学术会议 年份：2014
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[会议论文] 作者：Xu Zhang,Cheng Zhang,Shi-long Zhong,Zhi-wei Zhang,Yu-fen Li,
来源：第17届中国南方国际心血管病学术会议 年份：2015
Objective The basic helix-loop-helix transcription factor Hand2 plays an essential role in cardiac morphogenesis.Two microRNAs, miR-1 and miR-133, has been identified to inhibit Hand2 expression in ca...
Phosphoinositide-3-kinase, catalytic, alpha polypeptide RNA interference inhibits growth of colon ca
[期刊论文] 作者：Wen-Sheng Huang,Tian-Bao Wang,Yao He,Yu-Jun Chen,Shi-Long Zhong,Min Tan,
来源：世界胃肠病学杂志（英文版） 年份：2012
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[会议论文] 作者：Xinxin LI,Hao-ming Lin,Guo-dong HE,Shi-long ZHONG,Han-ping LI,Hai-Yan LAO,Xi-yong YU,
来源：第17届中国南方国际心血管病学术会议 年份：2015
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Site-specific hypomethylation within promoter CpG island of PON1 was associated with bleeding events
[会议论文] 作者：Shi-long ZHONG,Yan-hong KANG,Ji-yan CHEN,Xin-xin LI,Ying ZHANG,Hai-yan LAO,Xi-yong YU,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: To evaluate the role of the DNA methylation of the CpG island within the PON1 promoter on the clinical efficacy of the dual-antiplatelet therapy of aspirin and clopidogrel in patients with CAD af...
[会议论文] 作者：Xinxin LI,Hao-ming Lin,Guo-dong HE,Han-ping LI,Hai-Yan LAO,Xi-yong YU,Shi-long ZHONG,
来源：第17届中国南方国际心血管病学术会议 年份：2015
Purposes To evaluate the effect of the cytochrome P450 (CYP) 3A5 polymorphisms on the CYP3A activity and the activation of the clopidogrel in human liver S9 fraction.Methods CYP3A5 * 3 genotypes of 40...
Genotype and haplotype association of PON1with susceptibility to coronary artery diseaseand clinical
[会议论文] 作者：Yan-Hong Kang,Hai-Yan Lao,Hong Wu,Wei-Hua Lai,Xin-Xin Li,Xi-Yong Yu,Ji-Yan Chen,Shi-Long Zhong,
来源：中国药理学会第三届全国治疗药物监测学术年会 年份：2013
Aim: To evaluate the association of PON1 genetic variants with the susceptibility to coronary artery disease (CAD) as well as clinical endpoints in aspirin...
Plasma miR-126 as a potential marker predicting major adverse cardiac events in patients after percu
[会议论文] 作者：Xi-Yong Yu,Ji-Yan Chen,Hong Wu,Zhi-Wei Zheng,Zhi-Hong Chen,Xin-Xin Li,Ya-Ling Han,Shi-Long Zhong,
来源：第二届全国治疗药物监测学术年会 年份：2012
Background:Circulating miRNAs have been considered as promising novel biomarkers for prognosis of cardiovascular diseases.The present study was aimed to eva...
Hypomethylation within PON1 promoter CpG island was associated with bleeding events in dual antiplat
[会议论文] 作者：Shi-Long Zhong,Yan-Hong Kang,Ji-Yan Chen,Zhi-Xin Shan,Xi-Pei Wang,Guo-Dong He,Hai-Yan Lao,Xi-Yong Yu,
来源：中国工程院2014年医学科学前沿论坛第十四次全国临床药理学学术会议暨第六届国际药物警戒与药物安全学术会议 年份：2014
To evaluate the role of the DNA methylation of the CpG island within the PON1 promoter on the clinical efficacy of the dual-antiplatelet therapy of aspirin and clopidogrel in patients with CAD after p...
Genotype and haplotype association of PON1 with susceptibility to coronary artery disease and clinic
[会议论文] 作者：Yan-hong KANG,Hai-yan LAO,Hong WU,Wei-hua LAI,Xin-xin LI,Xi-yong YU,Ji-yan CHEN,Shi-long ZHONG,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: To evaluate the association of PON1 genetic variants with the susceptibility to coronary artery disease (CAD) as well as clinical endpoints in aspirin and clopidogrel dual antiplatelet-treated Ha...
,Influences of an NR1I2 polymorphism on heterogeneous antiplatelet reactivity responses to clopidogr
[期刊论文] 作者：Yi-bei Chen,Zi-yi Zhou,Guo-min Li,Can-xing Xiao,Wei-bang Yu,Shi-long Zhong,Ye-feng Cai,Jing Jin,Min Huang,
来源：中国药理学报（英文版） 年份：2019
Pregnane X receptor (PXR) is a member of nuclear receptor subfamily 1 (NR1I2) that is a transcriptional regulator of several metabolic enzymes involved in clopi...
SLCO1B1 521TC polymorphism associated with rosuvastatin-induced myotoxicity in Chinese coronary arte
[会议论文] 作者：Ju-E Liu,Xiao-Ying Liu,Sheng Chen,Yan Zhang,Li-Yun Cai,Min Yang,Wei-Hua Lai,Bin Ren,Shi-Long Zhong,
来源：2018第23届广东省药师周大会 年份：2017
Purpose This nested case-control study aimed to evaluate the association of candidate genetic variants with statin-induced myotoxicity in Chinese patients w...
Plasma miR-126 as a potential marker predicting major adverse cardiac events in dual antiplatelet-tr
[会议论文] 作者：Xi-Yong Yu,Shi-Long Zhong,Ji-Yan Chen,Zhi-Wei Zheng,Hong Wu,Li-Wen Li,Zhi-Wei Zhang,Zhi-Hong Chen,Qiu-Xiong,
来源：中国药理学会药物临床试验专业委员会首届学术研讨会 年份：2013
Aims: Antiplatelet treatment could cause a change in plasma levels of platelet microRNAs (miRNAs).However, it is not clear whether the plasma level of platelet miRNAs can predict clinical outcomes of...
,Plasma miR-142 predicts major adverse cardiovascular events as an intermediate biomarker of dual an
[期刊论文] 作者：Wu,Ji-yan Chen,Chun-yu Deng,Wang-sheng Sheng,Yong-heng Fu,Xiao-hong Li,Yu-bi Lin,Ya-ling Han,Shi-long Zhong,
来源：中国药理学报（英文版） 年份：2019
MicroRNAs (miRNAs) are widely expressed in organisms and are implicated in the regulation of most biological functions.The present study investigated the associ...
,Effects of SLCO1B1 and GATM gene variants on rosuvastatin-induced myopathy are unrelated to high pl
[期刊论文] 作者：Wang,Guan-lei Wang,Jia-li Li,Ding-sheng Wen,Xing-zhen Long,Hong-shuo Sun,Yi-bin Liu,Min Huang,Shi-long Zhong,
来源：中国药理学报（英文版） 年份：2019
Myotoxicity is a significant factor contributing to the poor adherence and reduced effectiveness in the treatment of statins.Genetic variations and high drug pl...
The independent contribution of miRNAs to the missing heritabil-ity in CYP3A4/5 functionality and th
[会议论文] 作者：Qian-Jie Tang,Xi-ao-Ying Liu,Xin Li,Xue Bai,Wan-Ping Zhong,Jin-Xiu Meng,Hao-Ming Lin,Ji-Yan Chen,Shi-Long Zhong,
来源：第18届中国南方国际心血管病学术会议 年份：2016
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The independent contribution of miRNAs to the missing heritability in CYP3A4/5 functionality and the
[会议论文] 作者：Tang,Xiao-Ying Liu,Xin Li,Xue Bai,Wan-Ping Zhong,Jin-Xiu Meng,Hao-Ming Lin,Hong Wu,Ji-Yan Chen,Shi-Long Zhong,
来源：2017年广东省药师周大会 年份：2016
To evaluate the independent contribution of miRNAs to the missing heritability in CYP3A4/5 functionality and atorvastatin metabolism,the relationships among three levels of factors,namely(1)clinical c...
A genome-wide association study identifies novel genetic loci modifying pharmacokinetic-pharmacodyna
[会议论文] 作者：Shi-Long Zhong,Ji-Yan Chen,Xin-Xin Li,Hao-Ming Lin,Hong Wu,Bin Zhang,Zhi-Wei Zhang,Dun-Liang Ma,Shuo,
来源：第五届全国治疗药物监测学术年会 年份：2015
Clopidogrel therapy is associated with a substantial variability in pharmacokinetics (PK) and pharmacodynamics (PD) responses.To date, known gene variants explain only a small proportion of the variab...
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