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[期刊论文] 作者:Yong-Chuan Wang,Sheng-Qiang Yu, 来源:亚洲男性学杂志:英文版 年份:2011
前列腺癌症(PCa ) 是年龄相关的疾病,并且 stromal 微型环境在 prostatic 起一个重要作用恶意的前进。然而,在在年轻、旧的织物在场的前列腺 stromal 房间的差别仍然是阴暗的。...
[期刊论文] 作者:Sheng-Qiang Yu,Kuo-Pao Lai,Shu, 来源:亚洲男性学杂志:英文版 年份:2009
雄激素受体(AR ) 在前列腺癌症(PCa ) 的发展和前进起一个重要作用。雄激素剥夺治疗在堵住肿瘤生长是开始有效的,但是它最后导致荷尔蒙倔强的状态。到雄激素独立的从雄激素依...
[期刊论文] 作者:Sheng-Qiang Yu,Kuo-Pao Lai,Shu-Jie Xia,Hong-Chiang Chang,Chawnshang Chang,Shuyuan Yeh, 来源:亚洲男性学杂志(英文版) 年份:2009
The androgen receptor (AR) plays an important role in the development and progression of prostate cancer (PCa).Androgen deprivation therapy is initially effective in blocking tumor growth,but it eventually leads to the hormonerefractory sta......
[期刊论文] 作者:Yong-Chuan Wang,Sheng-Qiang Yu,Xiao-Hai Wang,Bang-Min Han,Fu-Jun Zhao,Guang-Hui Zhu,Yan Hong,Shu-Jie, 来源:亚洲男性学杂志(英文版) 年份:2011
Prostate cancer (PCa) is an age-related disease,and the stromal microenvironment plays an important role in prostatic malignant progression.However,the differences in prostate stromal cells present in young and old tissue are still obscure.......
[期刊论文] 作者:Yue-Qing Tang,Bang-Min Han,Xin-Quan Yao,Yan Hong,Yan Wang,Fu-Jun Zhao,Sheng-Qiang Yu,Xiao-Wen Sun,Shu-Jie, 来源:亚洲男性学杂志(英文版) 年份:2009
Post-translational degradation of protein plays an important role in cell life.We employed chimeric molecules (dihydrotestosterone-based proteolysis-targeting chimeric molecule [DHT-PROTAC]) to facilitate androgen receptor (AR) degradation ......
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