Allergy-related Evidences in Relation to Serum IgE:Data from the China State Key Laboratory of Respi

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ObjectiveTo investigate the serum total IgE (tIgE) and specific IgE (sIgE) to common allergens among allergic patients in Guangzhou, China. Methods7 085 patients were examined for tIgE and sIgE to 15 allergens, based on the protocols of reversed enzyme allergosorbent test and the sandwich enzyme-linked immunosorbent assay. Results3 758(53.04%) patients tested positive for tIgE, and 4 640(65.49%) for sIgE.Der pteronyssinus,Der farinae, eggs, and cow’s milk were the most common allergens leading to higher positive rates of sIgE responses. Several peaks of sensitization were:Der pteronyssinus,Der farinae, and Blomia tropicalis at age 10-12; cow’s milk at age below 3; eggs at age 4-6. The mean level and positive rate of tIgE tended to increase in subjects sensitized to more allergens. Sensitization toDer pteronyssinus (OR, 1.6;P
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