近几年中,对于单一的抗风湿药反应不充分的类风湿性关节炎患者愈来愈多地采用选择性药物进行联合治疗,而药物相互并无有害的作用。众所周知,当两种或更多种具有多种药理作用的相似药物同时运用时,药物相互作用的危险性就增加。例如非肠道金制剂和D-青霉胺,由于这两种药物的毒性反应发生率都很高,故同时使用它们是不可取的。 In recent years, patients with rheumatoid arthritis who have not responded adequately to a single anti-rheumatic drug are increasingly using selective drugs for combination therapy, and drugs are not detrimental to each other. It is well known that when two or more similar drugs with multiple pharmacological actions are used simultaneously, the risk of drug interactions increases. Such as parenteral gold preparations and D-penicillamine, because both drugs have a high incidence of toxic reactions, it is not advisable to use them at the same time.