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目的调查长沙地区血液透析患者HCV感染高危因素,为临床预防控制HCV感染提供科学依据。方法对就诊于血液透析机构的115例HCV感染患者按1:1匹配的方式进行病例对照研究。结果透析治疗持续时间超过3年以上,有低蛋白血症,在3个或以上医疗机构接受过透析治疗的患者,其感染HCV的危险性分别是对照组的14.37倍、8.71倍和3.45倍。结论患有低蛋白血症、在多个医疗机构进行治疗以及透析治疗持续时间是长沙地区长期血液透析治疗患者感染HCV的主要危险因素。
Objective To investigate the risk factors of HCV infection in hemodialysis patients in Changsha and provide a scientific basis for clinical prevention and control of HCV infection. Methods A case-control study of 115 HCV-infected patients attending a hemodialysis facility at a 1: 1 match was performed. Results Patients with hypoproteinemia who had been treated for more than 3 years with dialysis had a risk of HCV infection of 14.37 times, 8.71 times and 3.45 times more than those of the control group, respectively, in patients receiving dialysis treatment in 3 or more medical institutions. Conclusions Hypoproteinemia, treatment in multiple medical institutions, and dialysis duration are the major risk factors for HCV infection in long-term hemodialysis patients in Changsha.