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目的了解糖尿病患者中脂肪性肝病的发生情况,为预防其发生及干预其发展提供依据。方法对130例糖尿病并发脂肪性肝病患者的病例资料进行回顾性分析。结果 130例糖尿病患者中代谢综合征79例,单纯脂肪肝56例,非酒精性脂肪性肝病82例,酒精性脂肪性肝病24例,肝功能异常者39例,Π型糖尿病中非酒精性脂肪性肝病高于Ι型糖尿病,代谢综合征中非酒精性脂肪性肝病占82.27%,酒精性脂肪性肝病占7.59%。结论糖尿病为代谢综合征的高危因素,有着共同发病基础的Ⅱ型糖尿病和代谢综合征,较易并发非酒精性脂肪性肝病。酒精性脂肪性肝病肝功能异常率明显高于非酒精性脂肪性肝病,提示长期大量饮酒更易造成肝脏损伤。而代谢综合征中酒精性脂肪性肝病发病较低,原因有待于进一步探讨。
Objective To understand the occurrence of fatty liver disease in diabetic patients and provide basis for preventing its occurrence and interfering with the development of fatty liver disease. Methods Retrospective analysis of 130 cases of patients with diabetes mellitus and fatty liver disease. Results Among 130 diabetic patients, there were 79 cases of metabolic syndrome, 56 cases of simple fatty liver, 82 cases of nonalcoholic fatty liver disease, 24 cases of alcoholic fatty liver disease, 39 cases of abnormal liver function, non-alcoholic fats in type Π diabetes Sexual liver disease is higher than type Ι diabetes mellitus, metabolic syndrome in non-alcoholic fatty liver disease accounted for 82.27%, alcoholic fatty liver disease accounted for 7.59%. Conclusions Diabetes mellitus is a risk factor of metabolic syndrome. It has type II diabetes mellitus and metabolic syndrome with common pathogenesis and is more likely to develop non-alcoholic fatty liver disease. Alcoholic fatty liver disease abnormal liver function was significantly higher than non-alcoholic fatty liver disease, suggesting that long-term heavy drinking more likely to cause liver damage. The metabolic syndrome in the lower incidence of alcoholic fatty liver disease, the reasons remain to be further explored.