心型脂肪酸结合蛋白是一种心肌高度特异蛋白质,在心肌损伤后短时间内释放入血,血浆浓度呈规律性变化,可作为急性冠状动脉综合征早期诊断的生化指标之一,心型脂肪酸结合蛋白临床检测方法的不断更新,为临床应用带来更多便捷.现就心型脂肪酸结合蛋白的生物学特性、检测方法、在急性冠状动脉综合征的临床应用进展做一综述.“,”Heart-type fatty acid-binding protein(H-FABP) is a myocardial highly specificity protein. It is known to be released rapid-ly from injured myocardium. The concentration of H-FABP is regularly fluctuated after myocardium injury. It can be regarded as one of bio-markers in the early diagnosis of acute coronary syndrome. Update of clinical detection methods of H-FABP brings more convenience for clini-cal application. This review focuses on the updated overview of the biological properties of H-FABP,detection methods,clinical application in acute coronary syndrome and the application prospect.