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探讨光学相干断层扫描仪(OpticalCoherenceTomography,OCT)后极部非对称性检查对青光眼的早期诊断价值.[方法]选取2015年1月至2018年1月于本院接受治疗的可疑开角型青光眼(SOAG)患者21例31眼,原发性开角型青光眼(POAG)患者23例33眼作为研究对象,同期选取于本院检测视力且健康者30例49眼作为对照组(CON组).比较三组受试者视野指标、视网膜神经纤维层厚度(RNFL)及后极部位视网膜厚度参数,分析POAG组和SOAG组患者视野平均缺损(visualfieldmeandefdct,MD)与后极部位视网膜厚度非对称性间相关性.[结果]SOAG组、CON组颞侧RNFL平均厚度、RNFL平均厚度、鼻侧RNFL平均厚度、上方RNFL平均厚度及下方RNFL平均厚度均显著高于POAG组,差异有统计学意义(P<0.05),CON组下方RN-FL平均厚度显著高于SOAG组,差异有统计学意义(P<0.05);SOAG组、CON组后极部位视网膜下方、上方及平均厚度均显著高于POAG组,差异有统计学意义(P0.05);CON组、POAG组及SOAG组视野MD分别是(1.43±1.03)dB、(-13.18±1.12)dB、(-1.69±1.04) dB,差异有统计学意义(P<0.05);Spearman相关分析显示,SOAG组患者D2、D3及D5与视野 MD有相关性, POAG组患者各个参数与视野 MD没有相关性.[结论]OCT可检测出SOAG患者后极部位视网膜厚度非对称性变化情况,对诊断前期开角型青光眼有一定帮助.“,”Toexplorethevalueofpost-polarasymmetryexaminationofopticalcoherencetomo-graphy(OCT)intheearlydiagnosisofglaucoma.[Methods]FromJanuary2015toJanuary2018,21patients(31 eyes)withsuspectedopenangleglaucoma(SOAG)and23patients(33eyes)withprimaryopenangleglaucoma (POAG)wereselectedasthestudysubjects.Atthesametime,30patients (49eyes)withvisualacuityand healthysubjectswereselectedasthecontrolgroup (CON group).Theparametersofvisualfieldindex,retinal nervefiberlayerthickness (RNFL)andretinalthicknessattheposteriorpolewerecomparedamongthethree groups.Thecorrelationbetweenmeanvisualfielddefect(MD)andasymmetryofretinalthicknessattheposterior poleinPOAGgroupandSOAGgroupwasanalyzed.[Results]ThemeanthicknessofRNFLintemporalside,RN-FLinnasalside,RNFLinupperpartandRNFLinlowerpartofCONgroupweresignificantlyhigherthanthose inPOAGgroup(P<0.05).ThemeanthicknessofRNFLinlowerpartoftheCONgroupwassignificantlyhigh-erthanthatintheSOAGgroup (P<0.05).TheposteriorretinathicknessoftheCONgroupwassignificantly higherthanthatofthePOAGgroup (P0.05).Thevisualfield MDoftheCONgroup,thePOAGgroupandtheSOAGgroup were(1.43±1.03)dB,(-13.18±1.12)dB,(-1.69 ±1.04)dB,respectively.Spearmancorrelationanalysis showedthatD2,D3andD5intheSOAGgroupwerecorrelatedwithvisualfieldMD,whileparametersinthePO-AGgroupwerenotcorrelatedwithvisualfieldMD.[Conclusion]OCTcandetecttheasymmetricchangesofretinal thicknessintheposteriorpoleofpatientswithSOAG,whichishelpfulforthediagnosisofearlyopen-angleglau-coma.