日前,困扰有机化学界多年的一个氮杂环化学合成难题,被南开大学的科研团队攻克。该校陈弓、何刚团队首次实现了对具有高“环张力”的苯并氮杂环丁烷类化合物的高效合成,填补了含氮杂环分子研究的一项重要空白。近日出版的英国《自然·化学》杂志发表了介绍该成果的论文。杂环化合物是由碳原子和非碳原子共同组成环状骨架结构的一类化合物。其中含有氮原子的环碳骨架是许多医 A few days ago, troubled by organic chemistry for many years a nitrogen heterocyclic chemical synthesis problem, was Nankai University’s research team to overcome. For the first time, the team of Chen Bow and He Gang realized the efficient synthesis of benzazepine compounds with high “ring tension ” and filled an important gap in the study of nitrogen-containing heterocyclic molecules. Recently published in the British “Nature · chemistry” magazine published a paper describing the results. Heterocyclic compounds are a class of compounds composed of cyclic skeletons composed of carbon atoms and non-carbon atoms. Among them, the ring carbon skeleton containing a nitrogen atom is a great many