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人MHCI类基因分两类:经典的Ia基因(包括HLA-A、HLA-B、HLA-C)和非经典的Ib基因(主要包括HLA-E与HLA-G、HLA-F)。经典的HLA-I类基因集中在远离着丝点的一端,包括B、C、A三个座位,到1996年WHO命名委员会公布的HLAI类基因中,已发现HLA-A位点有61个复等位基因,B位点和C位点各有136
Human MHC class I genes fall into two categories: classical Ia genes (including HLA-A, HLA-B and HLA-C) and non-classical Ib genes (mainly including HLA-E and HLA-G and HLA-F). Classical HLA-I genes are concentrated at one end away from the centromere, including the three loci B, C, and A. In the HLAI class of genes published by the WHO Nomenclature Commission in 1996, 61 HLA-A loci have been found The allele, B site and C site each have 136