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目的 :观察并分析苄星青霉素治疗妊娠期梅毒的临床疗效。方法 :随机选取所在医院收治的41例妊娠期梅毒孕产妇作为观察组,所有患者均于产前采用苄星青霉素进行治疗。同时,选择41例妊娠期梅毒孕产妇作为对照组,本组患者产前未给予苄星青霉素进行治疗,比较2组患者妊娠结局及新生儿状况。结果 :观察组妊娠不良结局发生率为17.07%,明显低于对照组(63.41%),2组差异具有统计学意义(P<0.05);观察组患者娩出健康新生儿37例,对照组娩出健康新生儿24例;观察组新生儿新生儿窒息、低体重儿、呼吸窘迫综合征发生率均明显低于对照组,2组差异明显(P<0.05)。结论:于妊娠期梅毒患者产前采用苄星青霉素进行治疗,可有效减少妊娠不良结局发生率,并在此基础上减少新生儿患病率,值得临床推广。
Objective: To observe and analyze the clinical efficacy of benzathine penicillin in the treatment of gestational syphilis. Methods: Forty-one pregnant women with syphilis during pregnancy were selected randomly as the observation group. All patients were treated with benzathine penicillin before the operation. At the same time, select 41 cases of pregnant women with gestational syphilis as a control group, this group of patients were not given antenatal penicillin for treatment, pregnancy outcomes and neonatal status in two groups were compared. Results: The incidence of adverse pregnancy outcomes in the observation group was 17.07%, which was significantly lower than that in the control group (63.41%). The difference between the two groups was statistically significant (P <0.05). In the observation group, 37 healthy newborns were delivered and the control group Neonates in 24 cases; neonatal asphyxia neonatorum in observation group, low birth weight infants, respiratory distress syndrome incidence were significantly lower than the control group, 2 significant differences (P <0.05). Conclusion: Prenatal treatment of syphilis during pregnancy with benzathine penicillin can effectively reduce the incidence of adverse pregnancy outcomes and reduce the prevalence of newborns on the basis of this, which deserves clinical promotion.