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目的:观察分析二甲双胍治疗老年社区糖尿病的应用效果。方法:选择2014年11月到2016年3月期间在我社区中心门诊进行血糖监测和治疗的87例老年糖尿病患者为研究对象,随机将患者分为观察组(44例)、对照组(43例),对对照组患者采用瑞格列奈治疗,对观察组采用二甲双胍治疗,对比2组治疗效果。结果:治疗后,观察组患者空腹血糖、餐后2h血糖指标显著优于对照组,观察组患者不良反应发生率为6.8%(3/44),显著低于对照组的25.6%(11/43),差异显著(P<0.05)。结论:老年糖尿病患者应用二甲双胍治疗可有效改善患者血糖指标,且不良反应发生率低,值得进行推广使用。
Objective: To observe and analyze the effect of metformin in the treatment of elderly community diabetes. Methods: Eighty-seven elderly patients with diabetes mellitus who underwent blood glucose monitoring and treatment in our Community Center from November 2014 to March 2016 were randomly divided into observation group (44 cases), control group (43 cases ). The patients in the control group were treated with repaglinide, the patients in the observation group were treated with metformin, and the treatment effect was compared with the two groups. Results: After treatment, the fasting blood glucose in the observation group was significantly higher than that in the control group at 2h. The incidence of adverse reactions in the observation group was 6.8% (3/44), significantly lower than that in the control group (25/64) (11/43 ), Significant difference (P <0.05). Conclusion: The treatment of metformin in elderly patients with diabetes mellitus can effectively improve the patients’ blood glucose level, and the incidence of adverse reactions is low, so it is worth to promote the use of metformin.