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比较了每日口服补铁与2种高剂量肠外铁注射补充。共鉴定了220名妊娠妇女(单胎妊娠和血红蛋白在8%-11g%之间,怀孕期16-24周)并随机分为2组。A组每日口服铁元素100 mg,B组给予肌注250 mg山梨醇铁,间隔4-6周重复1次。在研究开始评价血指标,并在36周观察2组补铁后的作用。用SPSS软件10.1分析资料。研究结果显示,血红蛋白和血细胞比容变化的绝对值分别为:口服组(1.18±0.68)g%和(4.02±2.59)%,肠外组(1.34±0.77)g%和(4.93±3.65)%。肠外补铁后(104.3±79.2)μg/L与口服补铁(97.6±47.8)μg/L对照,血清铁蛋白显示明显上升具有统计学意义。2组的产后结果也进行了比较。结论为,2种治疗方案的血液学反应在生物学上是等效的,2种高剂量肌注铁在妊娠铁补充中可能是一种好的替代方案。
Compared daily oral iron supplementation with 2 high-dose parenteral iron supplements. A total of 220 pregnant women (singleton pregnancies and hemoglobin between 8% and 11%, and between 16 and 24 weeks of gestation) were identified and randomly assigned to two groups. Group A daily oral iron 100 mg, Group B intramuscular injection of 250 mg sorbitol iron, 4-6 weeks intervals repeated 1 time. Blood indices were evaluated at the start of the study, and the effects of iron supplementation in both groups were observed at 36 weeks. Using SPSS software 10.1 to analyze the data. The results showed that the absolute values of hemoglobin and hematocrit were 1.18 ± 0.68 g and 4.02 ± 2.59%, 1.34 ± 0.77 g and 4.93 ± 3.65% . Parenteral iron (104.3 ± 79.2) μg / L and oral iron (97.6 ± 47.8) μg / L of control, serum ferritin showed a significant increase statistically significant. Postpartum outcomes in the two groups were also compared. The conclusion is that the hematological response to the two treatment regimens is biologically equivalent and that two high doses of intramyocardial iron may be a good alternative to iron supplementation in pregnancy.