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一些病例报告表明放疗与胸腹膜的恶性间皮瘤有关,动物实验也发现放疗是胸腹膜恶性肿瘤的致瘤因素。但所有有关放射接触与人类恶性间皮瘤的资料都是个例报告,并无系统对照研究。为此,作者利用美国癌症协会“监控、流行病学及最终结果纲要”1973～1993年间登记的女性乳腺癌251 750例及霍奇金病13 743例进行回顾性研究,其中在初期治疗时作过放疗的乳腺癌为62 453例,占24.8％;接受过放疗的霍
Some case reports indicate that radiotherapy is associated with malignant mesothelioma of the thoracic and peritoneal membranes. Animal studies have also found that radiotherapy is a tumorigenic factor of malignant tumors of the thoracic and peritoneal peritoneum. However, all the data concerning radiation exposure and human malignant mesothelioma are case reports and there is no systematic control study. To this end, the authors used a retrospective study of 251,750 women with breast cancer and 13 743 cases of Hodgkin’s disease that were registered between 1973 and 1993 by the American Cancer Society’s “monitoring, epidemiology, and end-result outlines,” which were performed during initial treatment. There were 62 453 breast cancer patients who had undergone radiation therapy, accounting for 24.8%;