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ＳＭ ３９９７ＳＭ ３９９７是一种新的非苯并二氮杂 类选择性抗焦虑药，由住友公司和辉瑞公司研制。在大鼠脑膜结合研究中发现，其对５－ＨＴ１Ａ结合位点有很强的亲和力（Ｋｉ＝２８ｎｍ），而对多巴胺Ｄ－２和５－ＨＴ２结合位点的亲和力均较弱（Ｋｉ分别为６５０和...
SM 3997SM 3997 is a new non-benzodiazepine selective anti-anxiety drug developed by Sumitomo and Pfizer. It was found that there was a strong affinity for the 5-HT1A binding site (Ki = 28 nm) and a weak affinity for the dopamine D-2 and 5-HT2 binding sites in the rat brain meningo-junctional study 650 and ...