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目的观察一种戊二醛消毒液的杀菌效果及稳定性。方法采用载体浸泡杀菌试验和理化分析方法,对该戊二醛消毒液进行了实验室检测。结果该戊二醛消毒液浓度为22 g/L,内含2.5 g/L脂肪醇聚氧乙烯醚。以该消毒剂原液对载体上枯草杆菌黑色变种芽孢作用60 min,杀灭对数值>3.0;作用4 h以上,可达到完全杀灭。该戊二醛消毒液连续浸泡医疗器械14 d,其杀菌效果不下降;模拟现场试验对医疗器械浸泡60 min,对污染在器械上的枯草杆菌黑色变种芽孢杀灭对数值≥5.0,浸泡5 h可达到完全杀灭。该消毒液密封存放于37℃90 d,戊二醛含量下降率<10%。结论该戊二醛消毒液能在规范时间内有效杀灭细菌芽孢,加速试验性能稳定。
Objective To observe the bactericidal effect and stability of a glutaraldehyde disinfectant. Methods The carrier soaking sterilization test and physical and chemical analysis methods, the glutaraldehyde disinfectant for laboratory testing. Results The concentration of glutaraldehyde disinfectant was 22 g / L, containing 2.5 g / L of fatty alcohol polyoxyethylene ether. The disinfectant solution on the carrier of Bacillus subtilis black mutant spores 60min, kill the logarithm value> 3.0; role of 4 h or more, can be completely killed. The glutaraldehyde disinfectant continuously soaked the medical device for 14 days, and its bactericidal effect did not decrease. The simulated field test immersed the medical device for 60 minutes, and the bactericidal activity of Bacillus subtilis on the instrument was ≥5.0, soaked for 5 h Can be completely killed. The disinfectant sealed stored at 37 ℃ 90 d, glutaraldehyde content decreased by <10%. Conclusion The glutaraldehyde disinfectant can effectively kill bacterial spores in the standard time and accelerate the test of stable performance.