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目的探讨血清中乳酸脱氢酶(LDH)水平对肺癌诊断的意义及其与TNM分期的关系。方法采用酶促反应法连续监测肺癌患者血清中LDH的水平,用统计学方法分析。结果肺癌组血清乳酸脱氢酶水平明显升高,与正常对照组比较差异有统计学意义(P<0.05);患者血清中乳酸脱氢酶值中晚期明显高于早期,差异有统计学意义(P<0.05)。结论动态监测血清中LDH水平对肺癌的辅助诊断、预后判断有一定的参考价值。
Objective To investigate the significance of serum lactate dehydrogenase (LDH) level in the diagnosis of lung cancer and its relationship with TNM staging. Methods The levels of LDH in serum of patients with lung cancer were continuously monitored by enzymatic reaction method and analyzed by statistical methods. Results Serum lactate dehydrogenase levels in lung cancer patients were significantly higher than those in normal controls (P <0.05). The serum lactate dehydrogenase levels were significantly higher in early and late lactation patients (P <0.05) P <0.05). Conclusion The dynamic monitoring of serum LDH level has certain reference value for the diagnosis and prognosis of lung cancer.