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报道了云木香(Saussurea lappa)乙醇提取物对大白鼠甲状腺、肾上腺、胰腺和肝的组织学的影响,及对肝糖原、血糖和血浆胰岛素的作用。云木香乙醇提取物在口服给药第3天,血糖开始降低,第7天降到最低(56.57±4.35mg％)。在同一试验中,肝糖原含量显示双相的变化,最初同对照值相比,有上升趋势,随后持续下降。第3天肝糖原增加到肝组织的24.29±3.3mg/g,但14天肝糖原含量(6.86±1.35)比对照组低,然而,在试验的任一时刻,血浆胰岛素和肾上腺抗坏血酸浓度未见明显改变。用PAS试剂染色的肝横切面显示,最初是肝糖
The effects of Saussurea lappa ethanol extracts on the histology of thyroid, adrenal, pancreas, and liver in rats, and effects on hepatic glycogen, blood glucose, and plasma insulin were reported. On the 3rd day after oral administration of Ethanol Extract, the blood glucose began to decrease and reached the lowest value on the 7th day (56.57±4.35mg%). In the same experiment, hepatic glycogen content showed a biphasic change that initially showed an upward trend compared to the control value and then continued to decline. On the third day hepatic glycogen increased to 24.29±3.3 mg/g of liver tissue, but the 14-day hepatic glycogen content (6.86±1.35) was lower than the control group. However, plasma insulin and adrenal ascorbic acid concentration were measured at any time during the experiment. No significant change was seen. Liver cross-section stained with PAS reagent showed that it was initially glycogen