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目的探讨儿童分化型甲状腺癌的临床诊治方法。方法回顾分析68例儿童分化型甲状腺癌患者的临床资料。结果患者均行手术治疗。行患侧叶甲状腺大部分切除术51例,次全或全切除术17例;患侧中央区淋巴结清扫24例,功能性淋巴结清扫36例,全淋巴结清扫8例。术后均行内分泌治疗。患者均获1～3年随访(其中4例3年后失访),均健在。结论儿童甲状腺癌的合理治疗方案仍然存在争议。外科手术为主要治疗手段,选择合理术式和术后辅助治疗可达满意疗效。
Objective To investigate the clinical diagnosis and treatment of differentiated thyroid cancer in children. Methods The clinical data of 68 children with differentiated thyroid cancer were retrospectively analyzed. Results All patients underwent surgical treatment. Fifty-one patients underwent partial or total thyroidectomy, and 17 cases underwent subtotal or total resection. There were 24 cases of lymph node dissection in affected area, 36 cases of functional lymph node dissection and 8 cases of lymph node dissection. All patients underwent endocrine therapy. All patients were followed up for 1 to 3 years (4 of them were lost after 3 years). Conclusion The rational treatment of thyroid cancer in children is still controversial. Surgery as the main treatment, choose the appropriate surgical procedures and postoperative adjuvant therapy up to satisfactory results.