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目的:探讨异位妊娠药物保守治疗成功的影响因素。方法:选取我院2014年1月至2016年1月收治的180例异位妊娠药物保守治疗患者为研究对象,根据患者临床疗效分为成功组(130例)和失败组(50例)。观察比较两组患者的临床表现、B超检查结果、入院时血β-HCG水平、阴道流血情况及盆腔有无积液情况,分析影响药物保守治疗成功率的因素。结果:通过对两组患者的各项检查情况进行分析发现异位妊娠患者入院时的血清β-HCG水平、B超检查显示的妊囊大小、盆腔积液深度在很大程度上影响患者的药物治疗成功率(P<0.05);而患者的年龄、孕次是否存在阴道出血情况与停经天数均不会给药物治疗的成功率造成明显影响(P>0.05)。结论:患者血清β-HCG水平、盆腔包块直径的大小是导致异位妊娠药物保守治疗成功率的主要因素。因此,在临床上对异位妊娠患者进行药物治疗时,还要根据患者的临床症状和辅助检查结果,选择合适患者的治疗方案,从而提高药物治疗异位妊娠的成功率。
Objective: To investigate the influencing factors of conservative treatment of ectopic pregnancy. Methods: 180 patients with conservative treatment of ectopic pregnancy treated in our hospital from January 2014 to January 2016 were selected as the research object. According to the clinical efficacy, the patients were divided into the success group (130 cases) and the failure group (50 cases). The clinical manifestations, B-ultrasound findings, blood β-HCG levels at admission, vaginal bleeding and pelvic fluid loss were observed and compared between the two groups. Factors influencing the success rate of conservative treatment were analyzed. Results: By analyzing the examination results of two groups of patients, the level of serum β-HCG at admission, the size of pregnant fetus revealed by B-ultrasound and the depth of pelvic fluid largely influenced the patients’ medication (P <0.05). However, the patients’ age, vaginal bleeding at the second trimester, and the number of menopause days did not significantly affect the success rate of drug treatment (P> 0.05). Conclusion: The level of serum β-HCG and the diameter of pelvic mass are the main factors leading to the success rate of conservative treatment of ectopic pregnancy. Therefore, in the clinical treatment of patients with ectopic pregnancy, but also according to the patient’s clinical symptoms and laboratory tests to select the appropriate treatment options to improve the success rate of drug treatment of ectopic pregnancy.