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目的探讨妊娠合并梅毒的不良妊娠结局及其影响因素。方法收集2015年1月1日-2015年7月31日在某医院分娩的91例妊娠合并梅毒患者的临床资料,对其一般人口学特征、产科特征和临床特征等变量进行单因素分析和多因素分析。结果单因素分析结果显示,妊娠合并梅毒患者的年龄、母亲梅毒快速血浆反应素试验滴度和是否进行抗梅毒治疗与不良妊娠结局的发生有关。多因素分析的结果显示,妊娠合并梅毒患者的母亲梅毒快速血浆反应素试验滴度(OR=4.388,P=0.017)和是否进行抗梅毒治疗(OR=0.064,P=0.001)与不良妊娠结局相关。结论妊娠合并梅毒患者的母亲梅毒快速血浆反应素试验滴度≥1∶16以及未进行治疗是发生不良妊娠结局的危险因素。
Objective To investigate the adverse pregnancy outcome and its influencing factors in pregnancy complicated with syphilis. Methods The clinical data of 91 pregnant women with syphilis during pregnancy delivered from January 1, 2015 to July 31, 2015 in a hospital were collected. Univariate analysis was used to analyze the general demographic, obstetric and clinical features of the patients and more Factor analysis. Results The results of univariate analysis showed that the age of patients with syphilis in pregnancy, the serum titer of syphilis rapid plasma test and whether or not anti-syphilis treatment were associated with adverse pregnancy outcomes. Multivariate analysis showed that maternal syphilis with syphilis in pregnant women had significantly higher titer of syphilis (OR = 4.388, P = 0.017) and anti-syphilis treatment (OR = 0.064, P = 0.001) . Conclusion The syphilis syphilis in pregnant mothers with rapid titer of syphilis test ≥ 1: 16 and not treated is a risk factor for adverse pregnancy outcomes.