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目的:探讨甲亢合并周期性麻痹(TPP)的发病情况、临床特点及131碘治疗后的疗效分析。方法:回顾性分析36例甲亢合并TPP患者与43例甲亢不伴TPP患者的临床资料及131碘治疗后疗效。结果:甲亢合并TPP患者男性明显多于女性,其中尤以30～40岁的青壮年多见;甲亢合并TPP患者平均131碘治疗剂量明显低于对照组(P<0.01);经131碘治疗后,甲亢合并TPP患者与对照组在甲亢治愈率、甲减发生率上无显著性差异(P>0.05)。结论:甲亢合并TPP发病男性明显多于女性,与Graves病有明显区别。早期、正确诊断甲亢合并TPP,可避免延误对以周瘫为主要症状的甲亢患者诊治。131碘治疗是一种非常有效的治疗甲亢合并TPP的方法。
Objective: To investigate the incidence of hyperthyroidism complicated with periodic paralysis (TPP), clinical features and efficacy analysis after 131I treatment. Methods: The clinical data of 36 cases of hyperthyroidism with TPP and 43 cases of hyperthyroidism without TPP were retrospectively analyzed. Results: Hyperthyroidism with TPP was significantly more men than women, especially in young adults aged 30 to 40 years; Hyperthyroidism with TPP average 131 Iodine dose was significantly lower than the control group (P <0.01); after 131 Iodine treatment There was no significant difference in the incidence of hypothyroidism and hypothyroidism between hyperthyroidism and TPP patients (P> 0.05). Conclusion: The incidence of hyperthyroidism combined with TPP is significantly higher in males than in females, which is obviously different from Graves’ disease. Early diagnosis of correct diagnosis of hyperthyroidism combined with TPP, to avoid delays in diagnosis and treatment of hyperthyroidism as the main symptoms of peripheral paralysis. 131 Iodine therapy is a very effective method of treating hyperthyroidism with TPP.