棉酚作为男用口服避孕药已在国内各地临床试用,效果良好。为了满足临床扩大试用和今后推广应用,棉酚的提取和精制方法应考虑经济、简便、安全等几个方面。关于棉酚的提取虽然已有多种方法,但均有成本高、毒性大、操作繁等不利于大量生产的 Gossypol as male oral contraceptives in clinical trials across the country, the effect is good. In order to meet clinical trials to expand and promote the use of the future, gossypol extraction and refining methods should be considered economic, simple, safe and so on. Although the extraction of gossypol has been a variety of ways, but both high cost, toxicity, complex operation is not conducive to mass production