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聚乙二醇(PEG,I)是一种聚醚类线性高分子化合物。无论分子最多少,每一分子中都只有两个末端羟基。HO-(CH_2CH_2O-)_nCH_2CH_2OH I 1972年西德Mutter及Bayer利用其作为可溶性高分子支持剂于多肽合成,取得满意结果。之后Kster报道了它在核苷合成中的应用。近年来Bayer及Zheng等在聚乙二醇
Polyethylene glycol (PEG, I) is a polyether linear polymer. No matter how many molecules, each molecule has only two terminal hydroxyl. HO- (CH_2CH_2O -) _ nCH_2CH_2OH I 1972 West Germany Mutter and Bayer as their soluble polymer support for peptide synthesis, and achieved satisfactory results. Kster later reported its use in nucleoside synthesis. In recent years Bayer and Zheng et al in polyethylene glycol