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目的:探讨ICSI周期取卵日血清孕酮水平与可用胚胎数及妊娠结局的关系。方法:对289例超促排卵后经ICSI助孕的患者资料进行回顾性分析。结果:在预测取卵后d3可用胚胎数方面,取卵日血清孕酮水平与注射hCG日E2水平的相对风险度分别为1.83和1.39。使用受试者工作曲线,界定出预测取卵后d3可用胚胎数目<4的取卵日孕酮浓度是11.7ng/ml。取卵日孕酮水平较高的患者获得了更多的可用胚胎且差异显著,但妊娠结局并无差异。结论:取卵日血清孕酮水平与可用胚胎数目相关,但不影响新鲜ICSI周期妊娠结局。
OBJECTIVE: To investigate the relationship between serum progesterone levels and the number of available embryos and pregnancy outcomes during ICSI cycles. Methods: A retrospective analysis of 289 patients with ICSI-assisted pregnancy after ovarian hyperstimulation was performed. Results: The relative risk of serum progesterone level on ovum and E2 level on the day of hCG injection were 1.83 and 1.39, respectively. Using the working curve of the subjects, the predicted progesterone concentration on ovulation at day d3 of predicted embryo number <4 was 11.7 ng / ml. Patients with higher progesterone levels at ovulation received more available embryos with significant differences, but there was no difference in pregnancy outcomes. Conclusion: The serum progesterone level on ovulation day is related to the number of available embryos but does not affect the outcome of fresh ICSI cycle pregnancy.