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目的:研究分析奥曲肽、普萘洛尔对肝硬化上消化道出血的治疗效果及对患者机体血流动力学的影响。方法:将我院在2011年至2016年期间收治的160例肝硬化上消化道出血的患者作为研究对象,并随机分为对照组和观察组,对对照组采用常规治疗,对观察组采用奥曲肽和普萘洛尔联合治疗。结果:根据对比两组患者在接受不同药物治疗后的效果得出,实验组的有效率要明显高于对照组;且在患者血流动力学情况方面也要由于对照组,两组数据差异显著,具有统计学意义(P<0.05)。结论:采用奥曲肽和普萘洛尔联合治疗消化道出血的应用效果要明显优于常规的治疗方法,可以降低门脉血流量、缩短止血时间,实用性要明显高于临床上的常规药物,值得临床推广应用。
Objective: To study the effect of octreotide and propranolol on the treatment of upper gastrointestinal bleeding in cirrhosis and its influence on the hemodynamics of patients. Methods: A total of 160 patients with upper gastrointestinal hemorrhage treated in our hospital from 2011 to 2016 were randomly divided into control group and observation group. The control group was treated with conventional therapy. The patients in the observation group were treated with octreotide And propranolol combination therapy. Results: According to the comparison of the effects of two groups of patients after receiving different drug treatment, the experimental group’s efficiency was significantly higher than that of the control group; and the patients’ hemodynamic status was also due to the control group, with significant difference between the two groups , With statistical significance (P <0.05). Conclusion: The combination of octreotide and propranolol in the treatment of gastrointestinal bleeding is obviously superior to the conventional treatment, which can reduce the portal blood flow and shorten the time to hemostasis, and its practicability should be obviously higher than that of the conventional drugs, which is worth Clinical application.