人类染色体减数分裂前期配对是配子形成过程中的重要事件。染色体在减数分裂前期配对可能形成单价体、部分未配对二价体、交锁现象、非同源配对等多种异常。这些配对异常可能是导致卵细胞发育闭锁的重要原因,也可能导致生育力降低、非整倍体形成。X与Y减数在染色体分裂前期配对时不等交换可能导致性反转综合征。 The pre-meiotic pairing of human chromosomes is an important event in gametophyte formation. Chromosome pairing pre-meiotic may form monovalent, some unpaired bivalent, interlocking phenomenon, non-homologous pairing and other abnormalities. These paired anomalies may be important factors leading to oocyte developmental atresia, may also lead to reduced fertility, aneuploidy. Unequal exchange between X and Y subtractions during pre-chromosomal pairing can lead to reversal syndrome.