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患者男,22岁。自幼发现耳聋,语言障碍。6岁时发现甲状腺肿大,并逐渐增大,曾在某医院按甲状腺机能亢进药物治疗未见好转。查体:身高165厘米,体重56公斤,智力稍差,无突眼。甲状腺呈弥漫性肿大,未扪及结节,无压痛,随吞咽而上下移动,无血管杂音。心肺未见异常。肝脾未触及。病理反射未引出。实验室检查:甲状腺吸(131)~碘率2小时43％;4小时54％;24小时58％。过氯酸钾释放试验:30分钟49％;60分钟54％;120分钟55％。甲状腺扫描:甲状腺呈弥漫性肿大。血清总T_4值3.4微克％,总T_3值1.2毫微克/毫升;TSH值102微单位/毫升。甲状腺球蛋白抗体:固相放射免疫法阴性。电测听力检查:感觉神
Male patient, 22 years old. Since childhood, he found deafness and language problems. Goiter was found at 6 years of age, and gradually increased, in a hospital according to hyperthyroidism drug treatment did not improve. Physical examination: height 165 cm, weight 56 kg, mental retardation, no exophthalmos. Thyroid was diffuse enlargement, palpable nodules, no tenderness, up and down with swallowing move, no vascular noise. Heart and lung no abnormalities. Liver and spleen not touched. Pathological reflex did not lead. Laboratory tests: Thyroid suction (131) ~ 2 hours of iodine 43%; 4 hours 54%; 24 hours 58%. Chlorate release test: 49% for 30 minutes; 54% for 60 minutes; 55% for 120 minutes. Thyroid scan: thyroid was diffuse enlargement. Serum T_4 value 3.4 μg%, total T_3 value of 1.2 ng / ml; TSH value of 102 μl / ml. Thyroglobulin antibody: solid-phase radioimmunoassay negative. Electric hearing test: feeling God