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目的：探讨首发青少年重性抑郁障碍患者的脑磁图特点。方法对12例未治疗的首发青少年重性抑郁障碍患者进行脑磁图检查，分析慢波偶极子的分布特点。结果本组12例患者，其中2例未得出慢波偶极子的定位信息，另外10例患者慢波偶极子分布在左额叶2例、左侧颞叶3例、左颞顶枕叶交界处3例、双额颞顶叶交界区及右颞叶各1例。各脑区分布比较差异无显著性（P＞0．05）。结论首发青少年重性抑郁障碍患者的脑磁图慢波偶极子主要分布在左侧额颞叶，对临床诊断有一定的参考价值。“,”Objective To explore the magnetoencephalography (MEG) character‐istics of first‐episode juveniles with major depression (MD) .Methods MEG ex‐aminations were performed in 12 first‐episode untreated MD juveniles ,distribu‐tion characteristics of slow wave dipoles analyzed .Results Of 12 patients 2 ones didn’ t discover slow wave dipole location information ,slow wave dipoles of 2 ones located in left frontal lobe ,3 in left temporal lobe ,3 in the junction of left temporal ,parietal and occipital lobe ,1 in the junction of double frontal ,tem‐poral and parietal lobe and 1 in right temporal lobe .There were no significant differences in all encephalic regions distributions (P> 0 .05) .Conclusion The MEG slow wave dipoles of first‐episode juveniles with MD mainly distribute in left frontal and temporal lobe ,which has a certain reference value for clinical diag‐nosis .