原因不明习惯性流产约占自然流产的40％～67．6％［l·’］，对于这部分病例，从生殖免疫学角度人们进行了多方面病因探讨。其中母体抗父系HLA抗体被认为是维持妊娠成功的一种重要保护性抗体，而原因不明习惯性流产患者可能缺乏这种保护性抗体。本组对33例该类患者与12例晚期妊 Unidentified habitual abortion accounted for about 40% to 67.6% of spontaneous abortion [l], for this part of the case, from the perspective of reproductive immunology, a multi-faceted etiology. Among them, maternal anti-paternal HLA antibodies are considered to be an important protective antibody to maintain the success of pregnancy. However, unexplained habitual abortion patients may lack such protective antibodies. The group of 33 patients with such patients and 12 cases of late pregnancy