现有的各种脑卒中动物模型都是采用正常血压、无脑血管基础病变的动物来复制的,这与临床上发生广泛脑动脉硬化基础上的脑卒中相差甚远。易卒中型自发性高血压大鼠(SHRSP)无需任何外界诱因则可自发脑卒中,但遗传缺陷在其血压升高和血管损害方面起着决定性作用且难于喂养,价格昂贵,用于模拟研究脑卒中仍有诸多不足。为建立一种更接近临床 All existing animal models of stroke are replicated in animals with normal blood pressure and without underlying cerebral vascular disease, which is far from the stroke occurring on the basis of extensive cerebral arteriosclerosis in the clinic. Stroke-spontaneous spontaneously hypertensive rats (SHRSPs) spontaneously stroke without any external predisposition, but genetic defects play a decisive role in raising blood pressure and impairing blood vessels and are difficult to feed and expensive to simulate brain research There are still many deficiencies in stroke. To establish a more clinically relevant