Fahr氏病是一种原因不明疾病,表现为进行性智力障碍、癫痫发作、颅内多发钙化灶。国内报告甚少。本文报道2例,除上述症状外,还表现为锥体外系样不自主运动,伴脑血管畸形和骶柱裂先天发育异常,从而提示本病可能与先天发育障碍有关。 [例1] 男,35岁。患者自幼智力差,近5年常左偏头痛,服镇痛药可缓解。半月前早餐时突然抽搐发作,意识丧失,口吐白沫,2分钟后症状缓解。后 Fahr’s disease is an unexplained disease characterized by progressive mental retardation, seizures, multiple intracranial calcifications. Little domestic report. This article reports 2 cases, in addition to the above symptoms, but also showed extrapyramidal involuntary movement, with cerebrovascular malformations and sacral cleft birth congenital dysplasia, suggesting that the disease may be related to congenital dysplasia. [Example 1] Male, 35 years old. Patients with mental retardation, often left migraine in the past 5 years, taking analgesics can be alleviated. Half a month before breakfast suddenly twitch attack, loss of consciousness, foaming at the mouth, 2 minutes after the symptoms ease. Rear