本发明涉及一种磁共振成像造影剂的制备方法,特别是钆布醇和钆多利道的制备方法。本发明是以廉价的二乙烯三胺和氨基二乙醇作为起始原料,经简单的取代、环合、烷基化等反应和脱盐、离心、纯化等工序制成钆布醇或钆多利道,其中R1=R2=- The present invention relates to a method for preparing a magnetic resonance imaging contrast agent, in particular to a method for preparing Gadobutrol and Gadolinium Road. The invention takes the cheap diethylenetriamine and the amino diethanol as the starting materials to prepare the gadobutrol or the gaddin channel through the steps of simple substitution, cyclization, alkylation, desalting, centrifugation and purification, Where R1 = R2 = -