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To determine the possibility of blending 2,3,5-triiodobenzoic acid( TIBA) and poly(p-dioxanone)( PPDO) to produce X-ray visible PPDO filaments, melt-blended PPDO with different concentrations of TIB A was obtained. Several radiopaque filaments of PPDO polymer filled with radiopaque TIBA particles were prepared via melt-blending. Material properties of the composite filaments were investigated using various material characterization techniques,including scanning electron microscope(SEM), thermogravimetric analysis( TGA), X-Ray Diffraction(XRD), dynamic rheometry and micro-CT scan. In this article, the dispersion of TIB A in PPDO,the properties of the filament,and the ratio of PPDO and TIBA and the corresponding X-ray visibility in vivo were studied. SEM results showed the dispersion of the contrast imaging agent TIBA was relatively even in the PPDO polymer. Xray analysis in vitro confirmed the enhanced radiopacity of the filaments with respect to the pure PPDO filament. The presence of iodine element in the composite filament could allow the bioabsorbable material to be monitored in vivo, and made it potential to be used in biomedical applications.
To determine the possibility of blending 2,3,5-triiodobenzoic acid (TIBA) and poly (p-dioxanone) (PPDO) to produce X-ray visible PPDO filaments, melt-blended PPDO with different concentrations of TIB A was obtained. radiopaque filaments of PPDO polymer were prepared via melt-blending. Materials properties of the composite filaments were investigated using various material characterization techniques, including scanning electron microscope (SEM), thermogravimetric analysis (TGA), X-Ray Diffraction X-ray diffraction (XRD), dynamic rheometry and micro-CT scan. In this article, the dispersion of TIB A in PPDO, the dispersion of TIB A in PPDO, showed the dispersion of the contrast imaging agent TIBA was relatively even in the PPDO polymer. Xray analysis in vitro confirmed the radiofacacity of the filaments with respect to the pure iodine element in to be monitored in vivo, and made it potential to be used in biomedical applications.