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目的：探讨在透析前停止或减少胰岛素剂量对维持性血液透析糖尿病患者低血糖发生的影响。方法：选择我院血液透析中心维持性血液透析的糖尿病患者30例（均使用胰岛素治疗），随机分为观察组和对照组，每组15例。观察组在血液透析前停止或减少胰岛素剂量，对照组在血液透析前继续常规使用胰岛素剂量，观察所有患者透析过程中血糖变化情况。结果：观察组患者血液透析中低血糖发生率为6.67％，而对照组为46.67%，观察组低血糖发生率明显低于对照组( P<0.05)。结论：血液透析前停止或减少胰岛素剂量可有效减少维持性血液透析糖尿病患者的低血糖发生率，该法值得推广。“,”Objective: To explore the effects of stopping or reducing the dose of insulin predialysis on hypoglycemia occurrence in maintain hemodialysis patients with diabetes. Methods:Thirty maintenance hemodialysis patients with diabetes were col ected and randomly divided into observation group and control group, 15 cases each group. Patients were stopping or reducing the dose of insulin dose before hemodialysis in the observation group, patients were routine use of insulin dose before hemodialysis in the control group. The change of the blood glucose of al patients were observee during hemodialysis.Results: The incidence of hypoglycemia of patients in the observation group was 6.67% during hemodialysis, but which was 46.67% in the control group, the difference of which between two groups had statistical significance (P< 0.05). Conclusion: Stopping or reducing insulin dose before hemodialysis can effectively reduce the incidence of hypoglycemia for maintenance hemodialysis patients with diabetes, this tharepy is worthy of popularization.