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Mcl-1(myeloid cell leukemia-1)基因作为Bcl-2家族成员之一,在细胞的生存凋亡,周期及分化调控中起着重要的作用。Mcl-1基因与血液系统恶性肿瘤的发生和发展有着密切的关系。
As a member of Bcl-2 family, Mcl-1 (myeloid cell leukemia-1) gene plays an important role in the regulation of cell apoptosis, cycle and differentiation. Mcl-1 gene is closely related to the occurrence and development of hematological malignancies.