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目的了解目前海南省自1991年后再未发生登革热流行后人群的抗体水平,为登革热防治提供科学依据。方法2005～2006年采集海南省既往登革热不同流行强度地区健康人群血样931份和发热病人急性期血样81份,分别检测登革IgG和IgM抗体。结果被调查的931名健康人群中,13例登革IgG抗体阳性(1.4%),主要集中在既往登革热高发的地区,年龄最小的38岁,主要为农民和渔民,低发区未检出阳性,发热病人血样检出IgM抗体阳性2例。结论海南省自1991年来未发生登革热的流行,但目前既往流行区人群登革热抗体水平已降至非常低的水平,有再次发生大规模流行的可能。
Objective To understand the antibody levels of the population in Hainan province since 1991 after the dengue fever epidemic has not yet occurred and provide a scientific basis for the prevention and treatment of dengue fever. Methods A total of 931 blood samples from healthy people and 81 acute blood samples from febrile seasons were collected from 2005 to 2006 in Hainan Province. Dengue IgG and IgM antibodies were detected respectively. Results Among the 931 healthy people surveyed, 13 were positive for dengue IgG antibody (1.4%), mainly in areas with high incidence of dengue fever, the youngest 38 years old, mainly farmers and fishermen, but no positive results in low incidence areas , Fever in patients with blood samples detected IgM antibodies in 2 cases. Conclusion Hainan Province has not had any dengue fever epidemic since 1991, but the population of dengue fever antibody in past endemic areas has dropped to a very low level and there is a possibility of pandemic again.