作者通过喂养缺锌饲料建立了缺锌动物模型,发现大鼠缺锌后出现骨钙降低,骨X线摄片显示骨皮质变薄、骨密度降低,同时光镜下可见长骨骺端软骨细胞及肥大细胞减少,肥大细胞变小.由此提示缺锌同样能引起骨钙化障碍,且与维生索D缺乏时的骨钙化障碍表现相似,同时还可能引起软骨内成骨受损,阻碍长骨的增长。作者认为这可能是缺锌所致侏儒的原因。而及时补锌,缺锌造成的骨损害可以治愈. The authors established a zinc deficiency animal model by feeding zinc-deficient feed. It was found that bone calcium was reduced after zinc deficiency in rats. Bone X-ray showed thin cortical bone and reduced bone density. At the same time, chondrocytes of the long bones were visible under light microscope. Mast cells decrease, mast cells become smaller. This suggests that zinc deficiency can also cause bone calcification disorders, and the performance of bone calcification in the absence of vitamin D is similar, but also may cause damage to the endochondral bone, impede the long bone increase. The author believes that this may be the reason for the dwarf caused by zinc deficiency. The timely addition of zinc, zinc deficiency caused by bone damage can be cured.