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久已知道,既有重症肌无力又患浸润性胸腺瘤的病人预后不良,作者收集此类病人19例予以分析。重症肌无力的诊断根据临床症状、药物反应及肌电图改变作出。浸润性胸腺瘤则依据活检、手术或尸解的病理切片。所有存活者作随访复查,特别注意现时用药、胸部X线检查和运动系统。这19例占493例重症肌无力病人的4%,占52例重症肌无力又有胸腺瘤者的37%。15例发现胸腺瘤前已有重症肌无力,4例产生肌无力前有纵隔前的症状。至今存活的8例,男女各半。除一例死于重症肌无力本身外,其余均死于呼吸循环衰竭或呼吸道感染。所有病例均无家族史。
A long time ago, both myasthenia gravis and patients with invasive thymoma poor prognosis, the authors collected 19 cases of such patients were analyzed. Myasthenia gravis diagnosis based on clinical symptoms, drug reactions and changes made by electromyography. Invasive thymoma is based on biopsy, surgical or autopsy pathology. All survivors were followed up for follow-up, paying particular attention to current medication, chest X-rays and motor systems. These 19 cases accounted for 4% of 493 cases of myasthenia gravis, 52 cases of myasthenia gravis and thymoma 37%. Fifteen patients had myasthenia gravis before thymoma, and four had pre-mediastinal symptoms before myasthenia gravis. So far 8 cases of survival, men and women in half. In addition to a case of death from myasthenia gravis itself, the rest died of respiratory failure or respiratory tract infection. All cases had no family history.