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通过经颞部结扎大鼠大脑中动脉及颈总动脉制备的局灶性脑梗塞模型，研究了盐酸小檗胺及脑血管扩张药“Ｘ”对脑缺血的保护作用。给药后，可缩小脑缺血面积，ＢＡ和“Ｘ”配伍应用效果好于单用。且改善脑缺血的同时可减轻脑水肿。
The cerebral ischemic model of cerebral infarction was induced by berberine hydrochloride and cerebral vasodilator drug “X” through focal cerebral infarction model of rat middle cerebral artery and common carotid artery. After administration, can reduce the ischemic area, BA and “X” compatibility effect is better than single use. And to improve cerebral ischemia can reduce cerebral edema.