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目的探讨硫必利联合感觉统合训练治疗抽动秽语综合征患儿的临床疗效。方法选取2010年12月至2015年12月韶关市第一人民医院儿童康复科收治的40例抽动秽语综合征患儿作为研究对象,按随机数字表法将其分为联合组和对照组,各20例。对照组患儿口服硫必利,联合组患儿在对照组基础上进行感觉统合训练,比较两组患儿临床疗效、治疗前及治疗后1、2、3个月耶鲁综合抽动严重程度量表(YGTSS)评分。结果联合组患儿治疗的总有效率显著高于对照组,差异有统计学意义(P<0.05);治疗后1、2、3个月,联合组患儿的YGTSS评分均明显低于对照组,差异均有统计学意义(均P<0.05)。结论硫必利联合感觉统合训练治疗抽动秽语综合征临床效果显著,可有效改善患儿临床症状,同时能减少长期服用药物对患儿产生的不良反应,安全性高。
Objective To investigate the clinical effect of combined therapy of tiapride and sensory integration in the treatment of children with Tourette’s syndrome. Methods Forty children with Tourette’s syndrome admitted to Children’s Rehabilitation Department of the First People’s Hospital of Shaoguan City from December 2010 to December 2015 were selected as the research objects and divided into the combined group and the control group according to the random number table 20 cases. Children in the control group were orally administered with tiapride, and the children in the combination group received sensory integration training on the basis of the control group. The clinical efficacy of the two groups was compared. Before and after treatment, the Yale comprehensive twitch severity scale (YGTSS) score. Results The total effective rate of treatment group was significantly higher than that of control group (P <0.05). After treatment, YGTSS scores of children in combination group were significantly lower than those in control group , The differences were statistically significant (all P <0.05). Conclusion The combination of tiapride and sensory integration therapy for the treatment of Tourette syndrome has a significant clinical effect, which can effectively improve the clinical symptoms of children and reduce the long-term adverse drug reactions to children with high safety.